Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR
Defects of mitochondrial DNA (mtDNA) are an important cause of disease and play a role in the ageing process. There are multiple copies of the mitochondrial genome in a single cell. In many patients with acquired or inherited mtDNA mutations, there exists a mixture of mutated and wild type genomes (...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12136116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf067 |
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