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A chemical enucleation method for the transfer of mitochondrial DNA to ρ° cells

The study of pathogenic mitochondrial DNA mutations has, in most cases, relied on the production of transmitochondrial cybrids. Although the procedure to produce such cybrids is well established, it is laborious and cumbersome. Moreover, the mechanical enucleation procedure is inefficient and differ...

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Main Authors: Bayona-Bafaluy, Maria Pilar, Manfredi, Giovanni, Moraes, Carlos T.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC169990/
https://ncbi.nlm.nih.gov/pubmed/12907750
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