Redox Regulation of Adenovirus-Induced AP-1 Activation by Overexpression of Manganese-Containing Superoxide Dismutase

Adenovirus gene therapy is a promising tool in the clinical treatment of many genetic and acquired diseases. However, it has also caused pathogenic effects in organs such as the liver. The redox-sensitive transcription factors AP-1 and NF-κB have been implicated in these effects. To study the mechan...

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Detalhes bibliográficos
Main Authors: Zhang, Hannah J., Drake, Victoria J., Xu, Linjing, Hu, Jianfang, Domann, Frederick E., Oberley, Larry W., Kregel, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135732/
https://ncbi.nlm.nih.gov/pubmed/11739700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.355-363.2002
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