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Manganese Superoxide Dismutase Modulates Hypoxia Inducible Factor-1 alpha Induction via Superoxide

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that plays an important role in O(2) homeostasis. Numerous observations suggest that changes in reactive oxygen species affect HIF-1α stabilization and HIF-1α transcriptional activation in many cell types. The antioxidant enzyme manganese...

詳細記述

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書誌詳細
主要な著者: Kaewpila, Suwimol, Venkataraman, Sujatha, Buettner, Garry R., Oberley, Larry W.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633869/
https://ncbi.nlm.nih.gov/pubmed/18413745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2635
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