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Redox manipulation of the manganese metal in human manganese superoxide dismutase for neutron diffraction

Human manganese superoxide dismutase (MnSOD) is one of the most significant enzymes in preventing mitochondrial dysfunction and related diseases by combating reactive oxygen species (ROS) in the mitochondrial matrix. Mitochondria are the source of up to 90% of cellular ROS generation, and MnSOD perf...

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Bibliografske podrobnosti
izdano v:Acta Crystallogr F Struct Biol Commun
Main Authors: Azadmanesh, Jahaun, Lutz, William E., Weiss, Kevin L., Coates, Leighton, Borgstahl, Gloria E. O.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168772/
https://ncbi.nlm.nih.gov/pubmed/30279321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18011299
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