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Redox manipulation of the manganese metal in human manganese superoxide dismutase for neutron diffraction

Human manganese superoxide dismutase (MnSOD) is one of the most significant enzymes in preventing mitochondrial dysfunction and related diseases by combating reactive oxygen species (ROS) in the mitochondrial matrix. Mitochondria are the source of up to 90% of cellular ROS generation, and MnSOD perf...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Azadmanesh, Jahaun, Lutz, William E., Weiss, Kevin L., Coates, Leighton, Borgstahl, Gloria E. O.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168772/
https://ncbi.nlm.nih.gov/pubmed/30279321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18011299
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