Residual Viral Replication during Antiretroviral Therapy Boosts Human Immunodeficiency Virus Type 1-Specific CD8(+) T-Cell Responses in Subjects Treated Early after Infection

Human immunodeficiency virus type 1 (HIV-1)-infected subjects treated early after infection have preserved HIV-1-specific CD4(+) T-cell function. We studied the effect of highly active antiretroviral therapy (HAART) on the frequency of HIV-1-specific CD8(+) T cells in patients treated during early (...

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Bibliographic Details
Main Authors: Ortiz, Gabriel M., Hu, Jennifer, Goldwitz, Joshua A., Chandwani, Rohit, Larsson, Marie, Bhardwaj, Nina, Bonhoeffer, Sebastian, Ramratnam, Bharat, Zhang, Linqi, Markowitz, Martin M., Nixon, Douglas F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135693/
https://ncbi.nlm.nih.gov/pubmed/11739706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.411-415.2002
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