Coupling of DNA Synthesis and Histone Synthesis in S Phase Independent of Cyclin/cdk2 Activity

DNA and histone synthesis are both triggered at the beginning of S phase by cyclin/cdk2 activity. Previous studies showed that inhibition of DNA synthesis with hydroxyurea or cytosine arabinoside (AraC) triggers a concerted repression of histone synthesis, indicating that sustained histone synthesis...

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Main Authors: Nelson, David M., Ye, Xiaofen, Hall, Caitlin, Santos, Hidelita, Ma, Tianlin, Kao, Gary D., Yen, Timothy J., Harper, J. Wade, Adams, Peter D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
DNA Dynamics and Chromosome Structure
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC135676/
https://ncbi.nlm.nih.gov/pubmed/12370293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7459-7472.2002
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