Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth

A calcineurin-nuclear factor of activated T cells (NFAT) regulatory pathway has been implicated in the control of cardiac hypertrophy, suggesting one mechanism whereby alterations in intracellular calcium handling are linked to the expression of hypertrophy-associated genes. Although recent studies...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wilkins, Benjamin J., De Windt, Leon J., Bueno, Orlando F., Braz, Julian C., Glascock, Betty J., Kimball, Thomas F., Molkentin, Jeffery D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135666/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.21.7603-7613.2002
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