Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth

A calcineurin-nuclear factor of activated T cells (NFAT) regulatory pathway has been implicated in the control of cardiac hypertrophy, suggesting one mechanism whereby alterations in intracellular calcium handling are linked to the expression of hypertrophy-associated genes. Although recent studies...

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Detalhes bibliográficos
Main Authors: Wilkins, Benjamin J., De Windt, Leon J., Bueno, Orlando F., Braz, Julian C., Glascock, Betty J., Kimball, Thomas F., Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135666/
https://ncbi.nlm.nih.gov/pubmed/12370307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7603-7613.2002
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