Depletion of Phosphatidylcholine in Yeast Induces Shortening and Increased Saturation of the Lipid Acyl Chains: Evidence for Regulation of Intrinsic Membrane Curvature in a Eukaryote

To study the consequences of depleting the major membrane phospholipid phosphatidylcholine (PC), exponentially growing cells of a yeast cho2opi3 double deletion mutant were transferred from medium containing choline to choline-free medium. Cell growth did not cease until the PC level had dropped bel...

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Hauptverfasser: Boumann, Henry A., Gubbens, Jacob, Koorengevel, Martijn C., Oh, Chan-Seok, Martin, Charles E., Heck, Albert J.R., Patton-Vogt, Jana, Henry, Susan A., de Kruijff, Ben, de Kroon, Anton I.P.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356607/
https://ncbi.nlm.nih.gov/pubmed/16339082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-04-0344
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