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A transmission disequilibrium test for general pedigrees that is robust to the presence of random genotyping errors and any number of untyped parents
Two issues regarding the robustness of the original transmission disequilibrium test (TDT) developed by Spielman et al are: (i) missing parental genotype data and (ii) the presence of undetected genotype errors. While extensions of the TDT that are robust to items (i) and (ii) have been developed, t...
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Huvudupphovsmän: | , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2004
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356564/ https://ncbi.nlm.nih.gov/pubmed/15162128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ejhg.5201219 |
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