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A transmission disequilibrium test for general pedigrees that is robust to the presence of random genotyping errors and any number of untyped parents

Two issues regarding the robustness of the original transmission disequilibrium test (TDT) developed by Spielman et al are: (i) missing parental genotype data and (ii) the presence of undetected genotype errors. While extensions of the TDT that are robust to items (i) and (ii) have been developed, t...

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Detalhes bibliográficos
Main Authors: Gordon, Derek, Haynes, Chad, Johnnidis, Christopher, Patel, Shailendra B, Bowcock, Anne M, Ott, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356564/
https://ncbi.nlm.nih.gov/pubmed/15162128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ejhg.5201219
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