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The ATPase activity of MCM2–7 is dispensable for pre-RC assembly but is required for DNA unwinding
Eukaryotes have six minichromosome maintenance (MCM) proteins that are essential for DNA replication. The contribution of ATPase activity of MCM complexes to their function in replication is poorly understood. We have established a cell-free system competent for replication in which all MCM proteins...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356333/ https://ncbi.nlm.nih.gov/pubmed/16369567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600892 |
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