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Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry

Herpes simplex virus (HSV) entry into cells requires binding of the envelope glycoprotein D (gD) to one of several cell surface receptors. The 50 C-terminal residues of the gD ectodomain are essential for virus entry, but not for receptor binding. We have determined the structure of an unliganded gD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Krummenacher, Claude, Supekar, Vinit M, Whitbeck, J Charles, Lazear, Eric, Connolly, Sarah A, Eisenberg, Roselyn J, Cohen, Gary H, Wiley, Don C, Carfí, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356314/
https://ncbi.nlm.nih.gov/pubmed/16292345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600875
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