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Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition

We report the identification of a novel protein that participates in Hedgehog-mediated patterning of the neural tube. This protein, named Tectonic, is the founding member of a previously undescribed family of evolutionarily conserved secreted and transmembrane proteins. During neural tube developmen...

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Autori principali: Reiter, Jeremy F., Skarnes, William C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356097/
https://ncbi.nlm.nih.gov/pubmed/16357211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1363606
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