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BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore

BMAP-28, a bovine antimicrobial peptide of the cathelicidin family, induces membrane permeabilization and death in human tumor cell lines and in activated, but not resting, human lymphocytes. In addition, we found that BMAP-28 causes depolarization of the inner mitochondrial membrane in single cells...

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書誌詳細
主要な著者: Risso, Angela, Braidot, Enrico, Sordano, Maria Concetta, Vianello, Angelo, Macrì, Francesco, Skerlavaj, Barbara, Zanetti, Margherita, Gennaro, Renato, Bernardi, Paolo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC135593/
https://ncbi.nlm.nih.gov/pubmed/11865069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1926-1935.2002
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