BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore

BMAP-28, a bovine antimicrobial peptide of the cathelicidin family, induces membrane permeabilization and death in human tumor cell lines and in activated, but not resting, human lymphocytes. In addition, we found that BMAP-28 causes depolarization of the inner mitochondrial membrane in single cells...

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Библиографические подробности
Главные авторы: Risso, Angela, Braidot, Enrico, Sordano, Maria Concetta, Vianello, Angelo, Macrì, Francesco, Skerlavaj, Barbara, Zanetti, Margherita, Gennaro, Renato, Bernardi, Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Cell Growth and Development
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC135593/
https://ncbi.nlm.nih.gov/pubmed/11865069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1926-1935.2002
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