BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore

BMAP-28, a bovine antimicrobial peptide of the cathelicidin family, induces membrane permeabilization and death in human tumor cell lines and in activated, but not resting, human lymphocytes. In addition, we found that BMAP-28 causes depolarization of the inner mitochondrial membrane in single cells...

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Main Authors: Risso, Angela, Braidot, Enrico, Sordano, Maria Concetta, Vianello, Angelo, Macrì, Francesco, Skerlavaj, Barbara, Zanetti, Margherita, Gennaro, Renato, Bernardi, Paolo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Cell Growth and Development
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC135593/
https://ncbi.nlm.nih.gov/pubmed/11865069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1926-1935.2002
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