BMAP-28, an Antibiotic Peptide of Innate Immunity, Induces Cell Death through Opening of the Mitochondrial Permeability Transition Pore

BMAP-28, a bovine antimicrobial peptide of the cathelicidin family, induces membrane permeabilization and death in human tumor cell lines and in activated, but not resting, human lymphocytes. In addition, we found that BMAP-28 causes depolarization of the inner mitochondrial membrane in single cells...

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Detalhes bibliográficos
Main Authors: Risso, Angela, Braidot, Enrico, Sordano, Maria Concetta, Vianello, Angelo, Macrì, Francesco, Skerlavaj, Barbara, Zanetti, Margherita, Gennaro, Renato, Bernardi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135593/
https://ncbi.nlm.nih.gov/pubmed/11865069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1926-1935.2002
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