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Mutations in the mitochondrial DNA D-loop region are frequent in cervical cancer

BACKGROUND: Mitochondrial DNA (mtDNA) is known for high mutation rates caused by lack of protective histones, inefficient DNA repair systems, and continuous exposure to mutagenic effects of oxygen radicals. Alterations in the non-coding displacement (D) loop of mitochondrial DNA are present in many...

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Autores principales: Sharma, Himani, Singh, Archna, Sharma, Chandresh, Jain, Sunesh Kumar, Singh, Neeta
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352382/
https://ncbi.nlm.nih.gov/pubmed/16359547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-5-34
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