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Mutations in the mitochondrial DNA D-loop region are frequent in cervical cancer

BACKGROUND: Mitochondrial DNA (mtDNA) is known for high mutation rates caused by lack of protective histones, inefficient DNA repair systems, and continuous exposure to mutagenic effects of oxygen radicals. Alterations in the non-coding displacement (D) loop of mitochondrial DNA are present in many...

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Autori principali: Sharma, Himani, Singh, Archna, Sharma, Chandresh, Jain, Sunesh Kumar, Singh, Neeta
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352382/
https://ncbi.nlm.nih.gov/pubmed/16359547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-5-34
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