Deoxysugar Transfer during Chromomycin A(3) Biosynthesis in Streptomyces griseus subsp. griseus: New Derivatives with Antitumor Activity

Chromomycin A(3) is an antitumor drug produced by Streptomyces griseus subsp. griseus. It consists of a tricyclic aglycone with two aliphatic side chains and two O-glycosidically linked saccharide chains, a disaccharide of 4-O-acetyl-d-oliose (sugar A) and 4-O-methyl-d-oliose (sugar B), and a trisac...

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Bibliographic Details
Main Authors: Menéndez, Nuria, Nur-e-Alam, Mohammad, Fischer, Carsten, Braña, Alfredo F., Salas, José A., Rohr, Jürgen, Méndez, Carmen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Physiology and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352227/
https://ncbi.nlm.nih.gov/pubmed/16391039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.72.1.167-177.2006
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