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The MexR Repressor of the mexAB-oprM Multidrug Efflux Operon in Pseudomonas aeruginosa: Characterization of Mutations Compromising Activity

Mutations in mexR yield a multidrug resistance phenotype in nalB mutants of Pseudomonas aeruginosa as a result of derepression of the mexAB-oprM multidrug efflux operon. MexR produced by several nalB strains carried single amino acid changes that compromised MexR stability or its ability to dimerize...

詳細記述

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書誌詳細
出版年:J Bacteriol
主要な著者: Adewoye, Lateef, Sutherland, Ainsley, Srikumar, Ramakrishnan, Poole, Keith
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12107151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.15.4308-4312.2002
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