The MexR Repressor of the mexAB-oprM Multidrug Efflux Operon in Pseudomonas aeruginosa: Characterization of Mutations Compromising Activity

Mutations in mexR yield a multidrug resistance phenotype in nalB mutants of Pseudomonas aeruginosa as a result of derepression of the mexAB-oprM multidrug efflux operon. MexR produced by several nalB strains carried single amino acid changes that compromised MexR stability or its ability to dimerize...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Principais autores:	Adewoye, Lateef, Sutherland, Ainsley, Srikumar, Ramakrishnan, Poole, Keith
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Gene Regulation
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12107151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.15.4308-4312.2002
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