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Genomic Disorders: Molecular Mechanisms for Rearrangements and Conveyed Phenotypes

Rearrangements of our genome can be responsible for inherited as well as sporadic traits. The analyses of chromosome breakpoints in the proximal short arm of Chromosome 17 (17p) reveal nonallelic homologous recombination (NAHR) as a major mechanism for recurrent rearrangements whereas nonhomologous...

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Bibliografiske detaljer
Main Authors: Lupski, James R, Stankiewicz, Pawel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352149/
https://ncbi.nlm.nih.gov/pubmed/16444292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010049
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