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Genomic Disorders: Molecular Mechanisms for Rearrangements and Conveyed Phenotypes

Rearrangements of our genome can be responsible for inherited as well as sporadic traits. The analyses of chromosome breakpoints in the proximal short arm of Chromosome 17 (17p) reveal nonallelic homologous recombination (NAHR) as a major mechanism for recurrent rearrangements whereas nonhomologous...

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Detalhes bibliográficos
Main Authors: Lupski, James R, Stankiewicz, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352149/
https://ncbi.nlm.nih.gov/pubmed/16444292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010049
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