Activation of Antibiotic Biosynthesis by Specified Mutations in the rpoB Gene (Encoding the RNA Polymerase β Subunit) of Streptomyces lividans

We found that the biosynthesis of actinorhodin (Act), undecylprodigiosin (Red), and calcium-dependent antibiotic (CDA) are dramatically activated by introducing certain mutations into the rpoB gene that confer resistance to rifampin to Streptomyces lividans 66, which produces less or no antibiotics...

詳細記述

書誌詳細

出版年:	J Bacteriol
主要な著者:	Hu, Haifeng, Zhang, Qin, Ochi, Kozo
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Genetics and Molecular Biology
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12081971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.14.3984-3991.2002
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