Alteration of Regiospecificity in Biphenyl Dioxygenase by Active-Site Engineering

Biphenyl dioxygenase (Bph Dox) is responsible for the initial dioxygenation step during the metabolism of biphenyl. The large subunit (BphA1) of Bph Dox plays a crucial role in the determination of the substrate specificity of biphenyl-related compounds, including polychlorinated biphenyls (PCBs). B...

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Hlavní autoři: Suenaga, Hikaru, Watanabe, Takahito, Sato, Mika, Ngadiman, Furukawa, Kensuke
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Enzymes and Proteins
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135152/
https://ncbi.nlm.nih.gov/pubmed/12057964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3682-3688.2002
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