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Family Shuffling of Soil DNA To Change the Regiospecificity of Burkholderia xenovorans LB400 Biphenyl Dioxygenase

Previous work has shown that the C-terminal portion of BphA, especially two amino acid segments designated region III and region IV, influence the regiospecificity of the biphenyl dioxygenase (BPDO) toward 2,2′-dichlorobiphenyl (2,2′-CB). In this work, we evolved BPDO by shuffling bphA genes amplifi...

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Autors principals: Vézina, Julie, Barriault, Diane, Sylvestre, Michel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797277/
https://ncbi.nlm.nih.gov/pubmed/17142386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01267-06
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