Nitric Oxide-Induced Homologous Recombination in Escherichia coli Is Promoted by DNA Glycosylases

Nitric oxide (NO(.)) is involved in neurotransmission, inflammation, and many other biological processes. Exposure of cells to NO(.) leads to DNA damage, including formation of deaminated and oxidized bases. Apurinic/apyrimidinic (AP) endonuclease-deficient cells are sensitive to NO(.) toxicity, whi...

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Detalhes bibliográficos
Main Authors: Spek, Erik J., Vuong, Laurel N., Matsuguchi, Tetsuya, Marinus, Martin G., Engelward, Bevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135131/
https://ncbi.nlm.nih.gov/pubmed/12057944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3501-3507.2002
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