Nitric Oxide-Induced Homologous Recombination in Escherichia coli Is Promoted by DNA Glycosylases

Nitric oxide (NO(.)) is involved in neurotransmission, inflammation, and many other biological processes. Exposure of cells to NO(.) leads to DNA damage, including formation of deaminated and oxidized bases. Apurinic/apyrimidinic (AP) endonuclease-deficient cells are sensitive to NO(.) toxicity, whi...

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Bibliographic Details
Main Authors: Spek, Erik J., Vuong, Laurel N., Matsuguchi, Tetsuya, Marinus, Martin G., Engelward, Bevin P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135131/
https://ncbi.nlm.nih.gov/pubmed/12057944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3501-3507.2002
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