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Homologous recombination prevents methylation-induced toxicity in Escherichia coli
Methylating agents such as N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) and methyl methane sulfonate (MMS) produce a wide variety of N- and O-methylated bases in DNA, some of which can block replication fork progression. Homologous recombination is a mechanism by which chromosome replication can proc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456334/ https://ncbi.nlm.nih.gov/pubmed/16670432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl222 |
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