Nitric Oxide-Induced Homologous Recombination in Escherichia coli Is Promoted by DNA Glycosylases

Nitric oxide (NO(.)) is involved in neurotransmission, inflammation, and many other biological processes. Exposure of cells to NO(.) leads to DNA damage, including formation of deaminated and oxidized bases. Apurinic/apyrimidinic (AP) endonuclease-deficient cells are sensitive to NO(.) toxicity, whi...

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Главные авторы: Spek, Erik J., Vuong, Laurel N., Matsuguchi, Tetsuya, Marinus, Martin G., Engelward, Bevin P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Genetics and Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC135131/
https://ncbi.nlm.nih.gov/pubmed/12057944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3501-3507.2002
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