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Macrophage tropism of HIV-1 depends upon efficient cellular dNTP utilization by reverse transcriptase
Retroviruses utilize cellular dNTPs to perform proviral DNA synthesis in infected host cells. Unlike oncoretroviruses, which replicate only in dividing cells, lentiviruses, such as HIV-1 and SIV, are capable of efficiently replicating in non-dividing cells (terminally differentiated macrophages) as...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2004
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351161/ https://ncbi.nlm.nih.gov/pubmed/15452123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M408573200 |
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