Macrophage tropism of HIV-1 depends upon efficient cellular dNTP utilization by reverse transcriptase

Retroviruses utilize cellular dNTPs to perform proviral DNA synthesis in infected host cells. Unlike oncoretroviruses, which replicate only in dividing cells, lentiviruses, such as HIV-1 and SIV, are capable of efficiently replicating in non-dividing cells (terminally differentiated macrophages) as...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Diamond, Tracy L., Roshal, Mikhail, Jamburuthugoda, Varuni K., Reynolds, Holly M., Merriam, Aaron R., Lee, Kwi Y., Balakrishnan, Mini, Bambara, Robert A., Planelles, Vicente, Dewhurst, Stephen, Kim, Baek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351161/
https://ncbi.nlm.nih.gov/pubmed/15452123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M408573200
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