Pyridoxal 5-Phosphate Inhibition of Substrate Selectivity Mutants of UhpT, the Sugar 6-Phosphate Carrier of Escherichia coli

In the sugar phosphate transporter UhpT, gain-of-function derivatives that prefer phosphoenolpyruvate (PEP) as substrate have an uncompensated lysine residue on transmembrane segment 11. We show here that these variants are also highly susceptible to substrate-protectable inhibition by covalent modi...

Полное описание

Библиографические подробности

Опубликовано в::	J Bacteriol
Главные авторы:	Hall, Jason A., Maloney, Peter C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Microbial Cell Biology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12057975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.13.3756-3758.2002
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