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Pyridoxal 5-Phosphate Inhibition of Substrate Selectivity Mutants of UhpT, the Sugar 6-Phosphate Carrier of Escherichia coli
In the sugar phosphate transporter UhpT, gain-of-function derivatives that prefer phosphoenolpyruvate (PEP) as substrate have an uncompensated lysine residue on transmembrane segment 11. We show here that these variants are also highly susceptible to substrate-protectable inhibition by covalent modi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2002
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135116/ https://ncbi.nlm.nih.gov/pubmed/12057975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3756-3758.2002 |
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