Pyridoxal 5-Phosphate Inhibition of Substrate Selectivity Mutants of UhpT, the Sugar 6-Phosphate Carrier of Escherichia coli
In the sugar phosphate transporter UhpT, gain-of-function derivatives that prefer phosphoenolpyruvate (PEP) as substrate have an uncompensated lysine residue on transmembrane segment 11. We show here that these variants are also highly susceptible to substrate-protectable inhibition by covalent modi...
Uloženo v:
| Vydáno v: | J Bacteriol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12057975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.13.3756-3758.2002 |
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