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A ROLE OF THE UBIQUITIN-PROTEASOME DEGRADATION PATHWAY IN THE BIOGENESIS EFFICIENCY OF β-CELL ATP-SENSITIVE POTASSIUM CHANNELS

ATP-sensitive potassium (K(ATP)) channels of pancreatic β-cells mediate glucose-induced insulin secretion by linking glucose metabolism to membrane excitability. The number of plasma membrane K(ATP) channels determines the sensitivity of β-cells to glucose stimulation. The K(ATP) channel is formed i...

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Detalhes bibliográficos
Main Authors: Yan, Fei-Fei, Lin, Chia-Wei, Cartier, Etienne A., Shyng, Show-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350484/
https://ncbi.nlm.nih.gov/pubmed/15987767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00240.2005
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