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A ROLE OF THE UBIQUITIN-PROTEASOME DEGRADATION PATHWAY IN THE BIOGENESIS EFFICIENCY OF β-CELL ATP-SENSITIVE POTASSIUM CHANNELS
ATP-sensitive potassium (K(ATP)) channels of pancreatic β-cells mediate glucose-induced insulin secretion by linking glucose metabolism to membrane excitability. The number of plasma membrane K(ATP) channels determines the sensitivity of β-cells to glucose stimulation. The K(ATP) channel is formed i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1350484/ https://ncbi.nlm.nih.gov/pubmed/15987767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00240.2005 |
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