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ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc

The ARF tumor suppressor participates in a p53-dependent apoptotic pathway that is stimulated in response to some oncogenic stimuli. The E2F1 transcription factor is a critical downstream target of the Rb tumor suppressor and, when active, can promote proliferation as well as apoptosis. The finding...

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Salvato in:
Pubblicato in:Mol Cell Biol
Autori principali: Russell, Jamie L., Powers, John T., Rounbehler, Robert J., Rogers, Pamela M., Conti, Claudio J., Johnson, David G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2002
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134697/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839803/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1360-1368.2002
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