ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc

The ARF tumor suppressor participates in a p53-dependent apoptotic pathway that is stimulated in response to some oncogenic stimuli. The E2F1 transcription factor is a critical downstream target of the Rb tumor suppressor and, when active, can promote proliferation as well as apoptosis. The finding...

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Главные авторы: Russell, Jamie L., Powers, John T., Rounbehler, Robert J., Rogers, Pamela M., Conti, Claudio J., Johnson, David G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Cell Growth and Development
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC134697/
https://ncbi.nlm.nih.gov/pubmed/11839803
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