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Papillomavirus E1 Protein Binds to and Stimulates Human Topoisomerase I
The papillomavirus (PV) E1 helicase plays a direct role in recruiting cellular DNA replication factors, such as replication protein A or polymerase α-primase, to replicate PV genomes. Here, E1 is shown to bind to human topoisomerase I and stimulate its relaxation activity up to sevenfold. The intera...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346965/ https://ncbi.nlm.nih.gov/pubmed/16415033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1584-1587.2006 |
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