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A Tick-Borne Langat Virus Mutant That Is Temperature Sensitive and Host Range Restricted in Neuroblastoma Cells and Lacks Neuroinvasiveness for Immunodeficient Mice

Langat virus (LGT), the naturally attenuated member of the tick-borne encephalitis virus (TBEV) complex, was tested extensively in clinical trials as a live TBEV vaccine and was found to induce a protective, durable immune response; however, it retained a low residual neuroinvasiveness in mice and h...

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Bibliografiset tiedot
Päätekijät: Rumyantsev, Alexander A., Murphy, Brian R., Pletnev, Alexander G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346960/
https://ncbi.nlm.nih.gov/pubmed/16415020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1427-1439.2006
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