Fine Structure and Activity of Discrete RAG-HMG Complexes on V(D)J Recombination Signals
Two lymphoid cell-specific proteins, RAG-1 and RAG-2, initiate V(D)J recombination by introducing DNA breaks at recombination signal sequences (RSSs). Although the RAG proteins themselves bind and cleave DNA substrates containing either a 12-RSS or a 23-RSS, DNA-bending proteins HMG-1 and HMG-2 are...
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| Publicado no: | Mol Cell Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1340-1351.2002 |
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