Fine Structure and Activity of Discrete RAG-HMG Complexes on V(D)J Recombination Signals

Two lymphoid cell-specific proteins, RAG-1 and RAG-2, initiate V(D)J recombination by introducing DNA breaks at recombination signal sequences (RSSs). Although the RAG proteins themselves bind and cleave DNA substrates containing either a 12-RSS or a 23-RSS, DNA-bending proteins HMG-1 and HMG-2 are...

Full description

Bibliographic Details

Published in:	Mol Cell Biol
Main Author:	Swanson, Patrick C.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2002
Subjects:	DNA Dynamics and Chromosome Structure
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1340-1351.2002
Tags:	Add Tag No Tags, Be the first to tag this record!