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Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms

The flavivirus nonstructural protein NS1 is a highly conserved secreted glycoprotein that does not package with the virion. Immunization with NS1 elicits a protective immune response against yellow fever, dengue, and tick-borne encephalitis flaviviruses through poorly defined mechanisms. In this stu...

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Autori principali: Chung, Kyung Min, Nybakken, Grant E., Thompson, Bruce S., Engle, Michael J., Marri, Anantha, Fremont, Daved H., Diamond, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346945/
https://ncbi.nlm.nih.gov/pubmed/16415011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1340-1351.2006
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