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Structure and Dynamics of Coxsackievirus B4 2A Proteinase, an Enyzme Involved in the Etiology of Heart Disease

The 2A proteinases (2A(pro)) from the picornavirus family are multifunctional cysteine proteinases that perform essential roles during viral replication, involving viral polyprotein self-processing and shutting down host cell protein synthesis through cleavage of the eukaryotic initiation factor 4G...

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Detalhes bibliográficos
Main Authors: Baxter, Nicola J., Roetzer, Andreas, Liebig, Hans-Dieter, Sedelnikova, Svetlana E., Hounslow, Andrea M., Skern, Tim, Waltho, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346940/
https://ncbi.nlm.nih.gov/pubmed/16415022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1451-1462.2006
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