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The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis.

The crystal structure of the 2A proteinase from human rhinovirus serotype 2 (HRV2-2A(pro)) has been solved to 1.95 A resolution. The structure has an unusual, although chymotrypsin-related, fold comprising a unique four-stranded beta sheet as the N-terminal domain and a six-stranded beta barrel as t...

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Bibliographic Details
Main Authors: Petersen, J F, Cherney, M M, Liebig, H D, Skern, T, Kuechler, E, James, M N
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171615/
https://ncbi.nlm.nih.gov/pubmed/10523291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5463
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