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Inactivation of cap-binding proteins accompanies the shut-off of host protein synthesis by poliovirus.
Infection of HeLa cells with poliovirus results in a rapid shut-off of host protein synthesis. It has been suggested that inactivation of a protein that binds to the cap structure of cellular mRNAs would explain the selective inhibition of host protein synthesis because the naturally uncapped poliov...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3447 |
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