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Inactivation of cap-binding proteins accompanies the shut-off of host protein synthesis by poliovirus.

Infection of HeLa cells with poliovirus results in a rapid shut-off of host protein synthesis. It has been suggested that inactivation of a protein that binds to the cap structure of cellular mRNAs would explain the selective inhibition of host protein synthesis because the naturally uncapped poliov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, K A, Sonenberg, N
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC346437/
https://ncbi.nlm.nih.gov/pubmed/6954488
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