Fanconi Anemia Proteins Are Required To Prevent Accumulation of Replication-Associated DNA Double-Strand Breaks

Fanconi anemia (FA) is a multigene cancer susceptibility disorder characterized by cellular hypersensitivity to DNA interstrand cross-linking agents such as mitomycin C (MMC). FA proteins are suspected to function at the interface between cell cycle checkpoints, DNA repair, and DNA replication. Usin...

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Bibliografiske detaljer
Main Authors: Sobeck, Alexandra, Stone, Stacie, Costanzo, Vincenzo, de Graaf, Bendert, Reuter, Tanja, de Winter, Johan, Wallisch, Michael, Akkari, Yassmine, Olson, Susan, Wang, Weidong, Joenje, Hans, Christian, Jan L., Lupardus, Patrick J., Cimprich, Karlene A., Gautier, Jean, Hoatlin, Maureen E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346898/
https://ncbi.nlm.nih.gov/pubmed/16382135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.425-437.2006
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