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Activation of the Epidermal Growth Factor (EGF) Receptor Induces Formation of EGF Receptor- and Grb2-Containing Clathrin-Coated Pits

In HeLa cells depleted of adaptor protein 2 complex (AP2) by small interfering RNA (siRNA) to the μ2 or α subunit or by transient overexpression of an AP2 sequestering mutant of Eps15, endocytosis of the transferrin receptor (TfR) was strongly inhibited. However, epidermal growth factor (EGF)-induce...

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Detaylı Bibliyografya
Asıl Yazarlar: Johannessen, Lene E., Pedersen, Nina Marie, Pedersen, Ketil Winther, Madshus, Inger Helene, Stang, Espen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346888/
https://ncbi.nlm.nih.gov/pubmed/16382132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.389-401.2006
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