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The Inhibitory Effect of ErbB2 on Epidermal Growth Factor-induced Formation of Clathrin-coated Pits Correlates with Retention of Epidermal Growth Factor Receptor-ErbB2 Oligomeric Complexes at the Plasma Membrane

By constructing stably transfected cells harboring the same amount of epidermal growth factor (EGF) receptor (EGFR), but with increasing overexpression of ErbB2, we have demonstrated that ErbB2 efficiently inhibits internalization of ligand-bound EGFR. Apparently, ErbB2 inhibits internalization of E...

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Main Authors: Haslekås, Camilla, Breen, Kamilla, Pedersen, Ketil W., Johannessen, Lene E., Stang, Espen, Madshus, Inger Helene
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289425/
https://ncbi.nlm.nih.gov/pubmed/16207817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-05-0456
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