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The Inhibitory Effect of ErbB2 on Epidermal Growth Factor-induced Formation of Clathrin-coated Pits Correlates with Retention of Epidermal Growth Factor Receptor-ErbB2 Oligomeric Complexes at the Plasma Membrane

By constructing stably transfected cells harboring the same amount of epidermal growth factor (EGF) receptor (EGFR), but with increasing overexpression of ErbB2, we have demonstrated that ErbB2 efficiently inhibits internalization of ligand-bound EGFR. Apparently, ErbB2 inhibits internalization of E...

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Detalhes bibliográficos
Main Authors: Haslekås, Camilla, Breen, Kamilla, Pedersen, Ketil W., Johannessen, Lene E., Stang, Espen, Madshus, Inger Helene
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289425/
https://ncbi.nlm.nih.gov/pubmed/16207817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-05-0456
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